I predicted Juggernaut a while ago and got slammed pretty heavily, but it's interesting that Dr. Strange references Cyttorak by using the Crimson Bands to try and restrain the Symbiote. So it's not so hard to push that perhaps maybe somehow just a little bit that it's a reference to potentially seeing the Crimson Gem of Cyttorak further down the line. They could have left any reference to Cyttorak out of the game entirely but instead chose to give it that one little plug, it seems more of a hint than a story element that we have a need to know that Dr. Strange has the Crimson Bands of Cyttorak.
And it's interesting that all this is happening in Earth-616.