Do you feel like doing a lot of work? I the proper way I would do this is completely break down your motherboard, just leave the ram and CPU seated.
Then I would clean the case, and look for any metal frays that may be laying around in the case. All it takes is one tiny metal fragment to do this. Use canned air all over the motherboard (away from the case), case, and card components - vid card, sound card, any other pci cards etc -
The analyze each and ever cable that connects to the mobo - usb headers, power supply cables, etc - make sure there arent any frayed ends or split wires.
Re-assemble carefully. You will the smallest amount of shift on the mobo, try and rest it as far away as possible from the pci brackets on the case (not out of line, just pull the mobo straight back when the mount screws are loose, and it wont allow much, maybe a mm or two) tighten every thing up, reconnect every thing, boot up and test.
Of the two grounding issues that killed my sound on two different PC’s - this corrected it. But its a shit ton of work too. A good 30 mins to an hour depending on how comfy you are doing it.