Taking out the X-Men and/or Fantastic Four franchises because of the Fox shit would suck. The series began with a X-Men only game, then it expanded. Dr. Doom is one of the most important villains in the Marvel universe, the character is really important.
Anyways, gimme my boy Gambit, my bro Cyclops and my waifu Psylocke back. Rogue, Colossus and Iceman are welcome too.