You should check out this thread. On pages 2 and I believe 3, Toodles does some comprehensive tests comparing a Microsoft Xbox 360 Wireless Game Pad against a Hori EX2 PCB and also an official PlayStation 3 SIXAXIS Game Pad against his own PS3 Cthulu board. They’re very interesting results!
The reality is that no, it won’t make a difference; wireless technology for video games has come a really long way and now you won’t have to worry about lag anymore. There are issues that come with using a wireless PCB though. You have to worry about the following:
-If your PCB isn’t one of the newer Microsoft common ground wireless controllers, you’ll have one hell of a time adding multi-console support in the future.
-In addition, you have to solder two wires to every button if it’s not a common ground, one for the ground of that specific button, the other for the signal.
-You’ll have to add a button somewhere on your stick to wire up the Sync button to from the wireless controller.
-You’ll have to purchase a Play & Charge kit and Microsoft’s rechargeable batteries to keep your controller alive. You could also just use regular batteries, but you’d have to open up your stick every time you want to replace them.
Oh, and whoever told you that having 11 buttons and a joystick on your stick would drain the battery faster lied to you. It’s a myth. Using arcade grade buttons doesn’t use any more energy than the little rubber contacts that Microsoft uses to activate their buttons.
In my opinion, most people just go wired due to convenience. I know I did; I absolutely did not wish to go through the hassle of hacking apart a Play & Charge kit, cutting out the plastic back of the Xbox 360 controller to host the battery, and drilling a new button hole for the Sync button.